Kantyna
The popularity of this place means you really should book. While popularity doesn't always translate into goodness, Kantyna bucks that trend. They have a great selection of sublime meat options, freshly prepared on the spot.
Ekant Indian restaurant
I don't think of Karlovo Namesti when going out. There's nothing wrong with it (even if it could look better) but it feels like there's so many better neighbourhoods to go to. If you think like me you'll miss the opportunity for some excellent #Indian food at Ekant.
The Miners
Am I the only surprised by the sudden appearance of The Miners almost everywhere I look? It feels like this coffee chain mushroomed out of nowhere, but it actually is a Czech success story with outlets from Madrid to Malta. The calming modern minimalist interior style pairs well with their choice of hipster drinks and/or coffee. Apart from something sweet, what else do you need from a modern-day coffee shop?
Orange bar
Tiny locations need to be great to survive, and finding these jewels is always worth the hunt. Orange Bar nestles behind the hustle and bustle of Dlouha's touristy side, serving amazing cocktails.
Pivo & Basilico Caffe Restaurant
The latest trend in Prague's foodie scene is to have Roman Pinsa on your menu. I don't mind that, but when everyone does it is it boring or fun? Pivo & Basilico merges Czech beer with an Italian menu and their pinsa is one of the better ones you can find locally.
Restaurace Hybernská
Unlike the majority of Czech restaurants in the centre, Restaurace Hybernská seems to focus on the local market not tourists. It's also enormous with space on 3 floors which tends to be packed on week day nights as well.
Rana
While the broad menu at Rana makes you think it's just another Indian restaurant, don't be fooled by that. Pakistani food is spiceier, moreish, and in some ways more savory than you'd expect.
Cantina nábřeží
Cantina continues Prague's increasing fascination with South American food. With an identical menu to their sister restaurant on Ujezd, this waterfront location is excellent for a post-dinner walk.
Cruz Cafe
From the brains behind the amazing Gran Fierro, comes a stylish bistro with a South-American vibe. They have great food options and many things are also available to take away, like their empanadas. Or their sour dough bread. Or their empanadas.
Cin cin wine bar
Apart from being centrally located, Cin Cin Wine Bar as a sommelier who is as knowledgeable as they come. They have a great line of Italian wines which pair well with their delicious platters imported from Italy. It's lovely to have (more) non-touristy options for a great evening out in the city centre.